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While research is still underway into the underlying causes of systemic and regional pain (also called “complex regional pain syndrome,” or CRPS-I or CRPS-II), we do know that chronic systemic and regional pain is frequently due to inflammatory or neurological side-effects of another health issue. It may arise following injury or trauma to part of your body, or it might be related to malfunctions in your nervous system. Systemic and regional pain also can occur in the presence of chronic diseases, particular those with autoimmune aspects.
The following common diagnoses are usually or often accompanied by significant and persistent pain which can disrupt every aspect of day-to-day life: