Systemic & Regional Chronic Pain


Does this describe your pain?

  • Deep muscle pain or morning stiffness
  • Chronic throbbing or aching pain felt “all over” or in specific areas of your body
  • Redness, warmth, or tender points on skin around the joints
  • Numbness or tingling in hands and feet
  • Pain that affects sleep quality
  • Lingering fatigue from daily activities, even after enough sleep
  • Associated with anxiety, moodiness, depression
  • Unable to tolerate hot or cold temperature extremes, or they make symptoms worse

Is your pain…

  •  Getting in the way of everyday activities and interrupting plans with family and friends
  • Causing you to lose time at work or to be unable to work consistently
  • Pervasive and persistent, making many parts of life intolerable
  • Resistant to other attempts at treatment

What causes most regional and complex pain?

While research is still underway into the underlying causes of  systemic and regional pain (also called “complex regional pain  syndrome,” or CRPS-I or CRPS-II), we do know that chronic systemic and  regional pain is frequently due to inflammatory or neurological  side-effects of another health issue. It may arise following injury or trauma to part of your body, or it might be related to malfunctions in your nervous system. Systemic and regional pain also can occur in the presence of chronic diseases, particular those with autoimmune aspects.

Which systemic and regional pain diagnoses are most common?

The following common diagnoses are usually or often accompanied by  significant and persistent pain which can disrupt every aspect of  day-to-day life:  

  • Fibromyalgia
  • Rheumatoid arthritis
  • Multiple sclerosis
  • Lupus
  • Addison’s disease
  • Graves’ disease
  • Hashimoto’s disease
  • Sjogren’s disease
  • Complications of Type 1 and Type 2 diabetes